Helle Krogh Johansen
Chief physician, Professor, DMSc
Department of Clinical Microbiology, Rigshospitalet; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen; Technical University of Denmark, Novo Nordisk Foundation Center for Biosustainability
The research area is (shared research between RH and DTU) persistent bacterial airway infections in patients with cystic fibrosis (CF). Most CF patients have bacteria in their lungs from early childhood until they die prematurely. The bacterial lung infections in CF patients, is an excellent model to study infectious disease for which antibiotic treatment is challenged by frequent lack of success. Equally important is that modern human life-style, as well as increases in the average population life span, will create problems with long-term bacterial infections that are difficult or impossible to treat. Moreover, the rising global problem of antibiotic resistance threatens to become the biggest health risk within the next 20-30 years. Our research is directly addressing the problem of antibiotic resistance in persistent bacterial infection.