Novo Nordisk Foundation Center for Protein Research
We are interested in obtaining novel understanding of the regulatory mechanisms in cell signaling. In particular, we are interested in unraveling the properties and the functional landscape of posttranslational modifications (PTMs) in signaling networks. Our group uses the latest genome editing technologies to generate engineered mammalian cell line models and applies the cutting-edge mass spectrometry-based proteomic technologies for unbiased, global, and quantitative analysis of key regulatory PTMs, including lysine acetylation and ubiquitylation. In this endeavour, the Group collaborates extensively with leading researchers from Denmark and around the world.