Institutionen för medicin, Karolinska Instiutet
Ingrid Dahlman is studying the role of the human abdominal subcutaneous adipose tissue depot in the development of insulin resistance. The amount and function of white adipose tissue is linked to insulin resistance and type 2 diabetes.
Ingrid Dahlman applies global transcriptome and DNA methylome profiling, as well as genetic association analyses, to define gene regulatory pathways in adipocytes that contribute to adipose tissue dysfunction and insulin resistance.
Ingrid Dahlman has recently reported a number of genes implicated in the regulation of body fat size and distribution, and adipose morphology, for example PLXND1 and LAMB3.