Peter Saliba-Gustafsson

Research Specialist

Karolinska Institutet, Stockholm, Sweden.

Biography

My research interests lie within the genetics of cardiometabolic diseases,
focussing on non-alcoholic fatty liver disease (NAFLD). I have a robust
background in genetic analyses of cardiometabolic traits, and surrogate
markers of cardiometabolic diseases. During my doctoral studies I explored
autophagy pathways in atherosclerosis, using candidate gene approaches. Main
findings included the discovery of a link between autophagy and
LXR-signalling, using genetic variants in the lipid droplet-associated
protein PLIN2 as a tool. During my postdoctoral training at Stanford
University I profiled myself within functional genomics, employing
large-scale single-cell CRISPRi screens to study genes suggested from
genome-wide association studies in relevant cell model systems. We have
established a functional genomic framework to study putative NAFLD-genes at
scale in a hepatocyte model system.

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