David Gaist

Professor and Consultant Neurologist

Department of Neurology, Odense University Hospital and the University of Southern Denmark, Odense

Biography

The principal research area of the clinical group is the epidemiology of stroke and other cerebrovascular disorders, particularly associations of these disorders with use of drugs.
Randomized clinical trials (RCTs) are the gold standard for proving drug efficacy. However, RCTs also leave many questions unanswered, e.g., regarding populations not studied in trials, interactions with other drugs or patient characteristics, and long-term effects of drugs beyond the typical trial duration. To bridge this knowledge gap, our group uses real-world data to study potential benefits and adverse effects of drugs on risk or prognosis of cerebrovascular disorders. Additionally, non-neurological effects of drugs that are used to treat or prevent cerebrovascular disorders are also investigated. The long-term goal is to provide evidence that will enhance physicians’ ability to individualize drug treatment for patients with cerebrovascular disorders.

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